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Quality Assurance: Free of endonuclease
X μL (10μg)
pseudouridine can reduce innate immune recognition compared with unmodified uridine and improve RNA stability and translational performance
and the methyl donor (SAM)
a 2’-O-tert-butyldimethylsilyl (TBDMS) protecting group for 2’-hydroxyl protection
DMT-2'-O-TBDMS-C(Ac)-CE Phosphoramidite Cap Analogs Quality Assurance: Free of endonucleaseDMT 2' O TBDMS C(Ac) CE Phosphoramidite is a protected ribonucleoside building block used for solid phase RNA oligonucleotide synthesis. It contains a 5' dimethoxytrityl (DMT) protecting group for 5' hydroxyl protection, a 2' O tert butyldimethylsilyl (TBDMS) protecting group for 2' hydroxyl protection, a cyanoethyl (CE) protecting group on phosphite, and a acetyl (Ac) base protecting group on cytosine. TBDMS offers excellent stability for protecting
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